CBD Roll-On | 4500 mg | CBD Roll on for Pain

CBD is the acronym for Cannabidiol, a non-psychoactive cannabinoid found in the Hemp plant. It is one of many compounds that have shown to have advantageous properties, without a psychotropic effect.While CBD is not yet FDA approved for any condition at this point and it is not intended to diagnose, treat, cure or prevent any disease, many studies have shown promising results.

Dosage depends on a variety of factors including; age, weight, individual biology, conditions you wish to address and other medications you maybe taking. Ultimately it depends on the goal an individual wishes to address. It is recommended to start off with a low dose and gradually increase as needed. There are no known adverse effects of over dosage and no known over doses with CBD, according to the World Health Organization in 2017.

We put together a chart as a reference and a starting point linked HERE.

CBD works on the regulatory system called Endocannabinoid system in the body. Our bodies produce cannabinoids similar to CBD and THC, naturally.

Our endogenous cannabinoid system, or Endocannabinoid system (ECS), has been discovered recently as a system of naturally occurring cannabinoids and cannabinoid receptor sites within our entire body! Endocannabinoids are naturally occurring in the brain that activate the same receptor sites as cannabinoids from the Cannabis plant.  Endocannabinoid system is active in many physiological processes.

Discovered in the late 1990s, the Endocannabinoid System, or ECS is a biological system found in all vertebrates; mammals and other species, composed of endocannabinoids and cannabinoid receptors. Initially, research has suggested that these receptors were only present in the brain and nerves but more recently scientist have found that these receptors exist throughout the body, including our skin, immune cells, bone, fat tissue, liver, pancreas, skeletal muscle, heart, blood vessels, kidney, and gastrointestinal tract. E

Endocannabinoids are endogenous neurotransmitters that are produced by our bodies. They regulate neurotransmission and allow for feedback loops. Anandamide and 2 Arachidonoylglycerol (2-AG) are the two primary Endocannabinoids.

The endocannabinoid system (ECS) is a biological system composed of lipid-based retrograde neurotransmitters that bind to cannabinoid receptors, and cannabinoid receptor proteins that are expressed throughout the central nervous system.

Research {source} has now shown that Endocannabinoid system is involved in a broad range of processes including:

In the International Journal of Molecular Sciences, March 19, 2018 article titled; Cannabinoid Receptors and the Endocannabinoid System: Signaling and Function in the Central Nervous System, the ECS is believed to have more cellular receptor sites than any other receptor system. The widespread distribution of these cannabinoid receptors shows just how important the ECS is to our overall bodily function and health.

Depending on the consumption type. Tinctures taken sublingually (under tongue) may take 15-30 minutes to take effect. Edibles and capsules may take 45 minutes to up to 1.5 hours. While vaping and smoking are more immediate, starting to take effect within 10 to 15 minutes.This is also dependent on personal biology, other medications one maybe taking, age and other factors.