In 1998, chemist Raphael Mechoulam and his peers made an amazing discovery: two key compounds in the human body increase the ability of a third compound (known as 2-AG) to bind to the main receptors of the body's Endocannabinoid System.
The Endocannabinoid System is responsible for numerous wellness-balancing processes in the human body. It's also the main system through which cannabis compounds like CBD and THC work. What's more, just like with 2-AG and its helper compounds, the compounds found in the cannabis plant have been shown to work together to help boost each other's wellness-balancing effects. This 'synergistic' (cooperative) relationship is so important that it even has its own name: the Entourage Effect. Famed cannabis researcher and neuroscientist Ethan Russo was the first to document the entourage effect in the cannabis plant in his groundbreaking 2010 review, Taming THC: potential cannabis synergy and phytocannabinoid-terpenoid entourage effects.
Scientists like Dr. Russo are continuing to reveal how the cooperative relationship that is the hallmark of the entourage effect helps maximize THC's and CBD's natural healing abilities.
Both CBD and THC have been shown to have numerous therapeutic benefits for mind-body health, including analgesic (pain-relieving) and neuroprotectant (nerve-protecting) effects. Research has shown that these compounds may also hold many other promising properties, including anti-bacterial, anti-inflammatory, anti-anxiety, anti-fungal, and other traits. That's why their ability to work together is so beneficial.
The cannabis plant has been used medicinally for centuries. It has been shown to be effective in treating a wide range of symptoms and conditions."
- American Nurses Association
Dr. Russo's initial research revealed that combining these ingredients together may have positive benefits for reducing inflammation, addressing anxiety, assisting in managing pain relief, fungal infections, epileptic seizures. In addition, research has shown that when CBD is added to THC, it may help reduce that compound's intoxicating effects.
A 2009 study of patients who were experiencing pain revealed that patients taking a mixture of CBD and THC (Sativex®) were almost twice as likely to experience a reduction in their pain symptoms than those taking just THC or a placebo.
Likewise, a 2018 meta analysis of 670 people with treatment-resistant epilepsy who were given CBD-rich cannabis extracts had a 25% greater reduction in the frequency of their seizures than those who were given pure CBD with no additional cannabinoids in it.
In addition, new evidence from a 2021 University of Arizona study found that combining four different cannabis terpenes with cannabinoids like CBD and THC elevated the entourage effect. The terpenes alpha-humulene, geraniol, linalool, and beta-pinene each exhibited greater pain-relieving effects when combined with a cannabinoid.
What's more, researchers may have finally figured out why combining cannabinoids like CBD and THC with terpenes helps produce the entourage effect. In a groundbreaking 2021 study it was shown that when CBD and terpenes interacted together, they produced higher levels of the precursor to CBD, CBDA. Researchers say this showed for the first time that different cannabis compounds interact to positively alter cannabinoid blood plasma levels for more potent effects.
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I purchased the Mega Gummy, CBD+THC gummies. WOW they are great, I never experienced something like this from hemp. They lasted a long time, gave a deep relaxing feeling yet was focused, didn't make me foggy and had a great night sleep. Totally different than taking THC alone. I am sold!
BETTER THAN THC ONLY GUMMIES
We don't currently have recreation dispensaries in our state yet, hopefully soon. I have to admit, it took me a minute to understand I can get these gummies delivered and be totally compliant. These are better than any THC gummy I have tried, doesn't make me anxious or crash.
UPLIFTING AND CALMING
Love these gummies. Great uplifting and calm feeling, also focused. Great for day time but also tried the 5:1 taking half or full gummy and had a great night's sleep.
“Eli Ruby ™ was founded with one clear goal: create true premium full spectrum hemp products that are rich with natural plant cannabinoids and other plant compounds, that are high efficacy, safe, tested and brings our customers great value and wellness."
As a Colorado company, we have been able to benefit from years of industry experience. We have been diligently perfecting how to effectively turn high-quality plants into premium finished wellness products.
We let science and outcomes guide our decisions and company direction. When it comes to our products, we are intentional and transparent. For us, integrity matters. We want to be who you turn to for trusted CBD & cannabinoids and CBD+THC.
Whether it is presenting lab verification that is easily accessible, clear labeling or helping our customers cultivate a wellness routine that’s right for them.
Our Commitment to Excellence is paramount to our business. When it comes to delivering a safe natural product, we follow best practices, attention to the details of what makes high quality hemp products that brings you the best of whole plant approach.
Our values are centered in providing the highest quality hemp products, educating, creating trust and loyalty with our customers, so you can feel confident in what you are buying.
“Cannabis is the single most versatile herbal remedy, and the most useful plant on Earth.”
– Ethan Russo, MD
We aim to deliver to you products with high efficacy and value with every step of development, treated as if it’s the most important one.
Our commitment to established best practices, safe and proper growing methods, genetic selection, processing and extraction techniques, to create products that brings the best out of this plant, is unmatched. Ultimately, when it comes to crafting the highest quality full spectrum CBD products, everything matters.
We pride ourselves in offering products that are all natural plant derived, never synthetic or chemical conversions of any kind, with quality ingredients, clean, safe, free of any toxins or pesticides, tested and verified hemp products.